A method is provided for operating a system to automatically conduct hygiene cycles for a confined space such an interior space of a box suitable for storing and/or carrying packaged food. The system may include a hygiene device that can be attached to the box to conduct the hygiene cycles and a mobile device that can wirelessly communicate with the hygiene device to control the conduction of the hygiene cycles. The method may include automatically collecting information related to the hygiene cycles using the hygiene device and transmitting the collected information to a network directly or through the mobile device.