- 专利标题: Method for depleting malignant T-cells
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申请号: US17832371申请日: 2022-06-03
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公开(公告)号: US11885807B2公开(公告)日: 2024-01-30
- 发明人: Martin Pulé , Paul Maciocia
- 申请人: AUTOLUS LIMITED
- 申请人地址: GB London
- 专利权人: AUTOLUS LIMITED
- 当前专利权人: AUTOLUS LIMITED
- 当前专利权人地址: GB London
- 代理机构: MARSHALL, GERSTEIN & BORUN LLP
- 优先权: GB 03905 2014.03.05 GB 16908 2014.09.25
- 主分类号: G01N33/574
- IPC分类号: G01N33/574 ; G16H50/30 ; C12Q1/6886 ; C12Q1/686 ; A61K39/00
摘要:
The present invention relates to a chimeric antigen receptor (CAR) which comprises an antigen-binding domain which selectively binds TOR beta constant region 1 (TRBC1) or TRBC2; cells; such a T cells comprising such a CAR; and the use of such cells for the treatment of a T-cell lymphoma or leukaemia in a subject.
公开/授权文献
- US20230018688A1 METHODS 公开/授权日:2023-01-19
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