Invention Grant
- Patent Title: Method for the synthesis of 2,4-dimethylpyrimidin-5-ol, intermediates, and method for the synthesis of Lemborexant using the intermediates
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Application No.: US17814815Application Date: 2022-07-25
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Publication No.: US11891375B2Publication Date: 2024-02-06
- Inventor: Abdeslam Akhatou , Alicia Dobarro Rodríguez
- Applicant: MOEHS IBERICA, S.L.
- Applicant Address: ES Barcelona
- Assignee: MOEHS IBERICA, S.L.
- Current Assignee: MOEHS IBERICA, S.L.
- Current Assignee Address: ES Barcelona
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: ES 202130723 2021.07.26
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07C201/14 ; C07D239/34 ; C07D239/36
Abstract:
A method is for the synthesis of 2,4-dimethylpyrimidin-5-ol, which can be used as an intermediate compound in the synthesis of Lemborexant. The method includes reacting a nitrophenyl compound with N,N-dimethylformamide diethyl acetal.
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