- 专利标题： Antibodies to carcinoembryonic antigen-related cell adhesion molecule (CEACAM)
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申请号： US17037136申请日： 2020-09-29
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公开(公告)号： US11891453B2公开(公告)日： 2024-02-06
- 发明人: Gal Markel , Tehila Ben Moshe , Yair Sapir , Ilana Mandel , Jacob Schachter , Rona Ortenberg
- 申请人： Famewave Ltd.
- 申请人地址： IL Rehovot
- 专利权人： FAMEWAVE LTD.
- 当前专利权人： FAMEWAVE LTD.
- 当前专利权人地址： IL Rehovot
- 代理机构： ROTHWELL, FIGG, ERNST & MANBECK, P.C.
- 优先权： WO TIL2011000808 2011.10.11
- 主分类号： C07K16/42
- IPC分类号： C07K16/42 ; C07K16/30 ; A61K35/17 ; A61K39/395 ; A61K45/06 ; G01N33/68 ; A61K39/00
摘要：
The present invention provides antibodies, as well as molecules having at least the antigen-binding portion of an antibody, recognizing a specific epitope of the protein CEACAM1 and optionally binds also other subtypes of the CEACAM protein family Disclosed antibodies and antibody fragments are characterized by specific CDR sequences. Methods of production and use in therapy and diagnosis, of such antibodies and antibody fragments are also provided.
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