公开(公告)号：US11891453B2

公开(公告)日：2024-02-06

申请号：US17037136

申请日：2020-09-29

申请人： Famewave Ltd.

发明人： Gal Markel ,  Tehila Ben Moshe ,  Yair Sapir ,  Ilana Mandel ,  Jacob Schachter ,  Rona Ortenberg

IPC分类号： C07K16/42 ,  C07K16/30 ,  A61K35/17 ,  A61K39/395 ,  A61K45/06 ,  G01N33/68 ,  A61K39/00

CPC分类号： C07K16/42 ,  A61K35/17 ,  A61K39/39566 ,  A61K45/06 ,  C07K16/3007 ,  G01N33/686 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92

摘要： The present invention provides antibodies, as well as molecules having at least the antigen-binding portion of an antibody, recognizing a specific epitope of the protein CEACAM1 and optionally binds also other subtypes of the CEACAM protein family Disclosed antibodies and antibody fragments are characterized by specific CDR sequences. Methods of production and use in therapy and diagnosis, of such antibodies and antibody fragments are also provided.