A reconfigurable wall panel system configured to enable rapid attachment and removal of a wide range of interchangeable wall units and accessories is disclosed. One or more embodiments comprise a reconfigurable wall panel having a wall frame with one or more design spaces, each design space having opposing upper and lower grooves and a depression serving as a fulcrum for insertion of interchangeable wall units. Embodiments of interchangeable wall units may include one or more facing features, as well as upper and lower edges corresponding to the opposing upper and lower grooves of the one or more design spaces, the interchangeable wall units being configured to tilt into the depression and slide into a removably secured position within the respective design space.