Invention Grant
- Patent Title: Pyridine macrocycle compounds as ASK1 inhibiting agents
-
Application No.: US17265986Application Date: 2019-08-13
-
Publication No.: US11897898B2Publication Date: 2024-02-13
- Inventor: Felix Gonzalez Lopez de Turiso
- Applicant: BIOGEN MA INC.
- Applicant Address: US MA Cambridge
- Assignee: BIOGEN MA INC.
- Current Assignee: BIOGEN MA INC.
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Xin Zhang
- International Application: PCT/US2019/046327 2019.08.13
- International Announcement: WO2020/036946A 2020.02.20
- Date entered country: 2021-02-04
- Main IPC: C07D498/22
- IPC: C07D498/22 ; A61K31/4741 ; C07D519/00

Abstract:
Provided are compounds of Formula (I′), including compounds of Formulas (I), (II), (III), (IIIA) and (IIIB), wherein L, R1, R3 and n are as defined herein, and pharmaceutically acceptable salts thereof, and methods for their use and production. These compounds can be useful, e.g., in the treatment of disorders responsive to the inhibition of apoptosis signal-regulating kinase 1 (ASK1).
Public/Granted literature
- US20210300946A1 PYRIDINE MACROCYCLE COMPOUNDS AS ASK1 INHIBITING AGENTS Public/Granted day:2021-09-30
Information query