- 专利标题： In vitro generation of thymic organoid from human pluripotent stem cells
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申请号： US16648008申请日： 2018-09-19
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公开(公告)号： US11898166B2公开(公告)日： 2024-02-13
- 发明人: Raul E. Vizcardo , Nicholas P. Restifo
- 申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 申请人地址： US MD Bethesda
- 专利权人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址： US MD Bethesda
- 代理机构： Leydig, Voit & Mayer, Ltd.
- 国际申请： PCT/US2018/051625 2018.09.19
- 国际公布： WO2019/060336A 2019.03.28
- 进入国家日期： 2020-03-17
- 主分类号： C12N5/078
- IPC分类号： C12N5/078 ; A61K35/26
摘要：
Disclosed are methods of preparing thymic organoids according to embodiments of the invention. Also disclosed are methods of preparing thymic emigrant cells in vitro, according to embodiments of the invention. Also disclosed are methods of treating or preventing a condition in a mammal, e g., cancer.
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