- 专利标题： Inhibitors of SARM1 NADase activity and uses thereof
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申请号： US17508321申请日： 2021-10-22
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公开(公告)号： US11903935B2公开(公告)日： 2024-02-20
- 发明人: Jeffrey Milbrandt , Kow Essuman , Yo Sasaki , Aaron Diantonio , Xianrong Mao , Rajesh Devraj , Raul Eduardo Krauss , Robert Owen Hughes
- 申请人： Washington University , Disarm Therapeutics, Inc.
- 申请人地址： US MO Saint Louis
- 专利权人： Washington University,Disarm Therapeutics, Inc.
- 当前专利权人： Washington University,Disarm Therapeutics, Inc.
- 当前专利权人地址： US MO Saint Louis; US MA Cambridge
- 代理商 Robert D. Shereda
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K47/55 ; A61K47/52 ; A61P25/28 ; A61K33/243 ; A61K31/047 ; A61K31/145 ; A61K31/198 ; A61K31/41 ; A61K31/437 ; A61K31/4375 ; A61K31/444 ; A61K31/4535 ; A61K31/566 ; A61K31/7048 ; A61K31/7084 ; A61K33/245 ; A61K33/28 ; A61K33/30
摘要：
The present disclosure provides compounds useful as inhibitors of SARM1 NADase activity, compositions thereof, and methods of using the same. The present disclosure provides compounds useful for treating a neurodegenerative or neurological disease or disorder, compositions thereof, and methods of using the same.
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