- 专利标题： Dual targeting and therapeutic nanoparticle for treating renal fibrosis
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申请号： US17452041申请日： 2021-10-22
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公开(公告)号： US11904021B2公开(公告)日： 2024-02-20
- 发明人: Chung Hang Jonathan Choi , Cecilia Ka Wing Chan , Yun Wong James Lau
- 申请人： The Chinese University of Hong Kong
- 申请人地址： CN Hong Kong
- 专利权人： THE CHINESE UNIVERSITY OF HONG KONG
- 当前专利权人： THE CHINESE UNIVERSITY OF HONG KONG
- 当前专利权人地址： CN Hong Kong
- 代理机构： Saliwanchik, Lloyd & Eisenschenk
- 主分类号： A61K47/69
- IPC分类号： A61K47/69 ; A61K33/242 ; A61K33/38 ; A61K33/26 ; A61P13/12 ; A61K33/243 ; A61K47/54 ; A61K9/51 ; A61K33/24
摘要：
The subject invention pertains to compositions and methods for making and use of metal-based coated nanoparticles. The metal-based, PEG-coated nanoparticles of the invention comprise folic acid molecules on their surface exercise dual functionality by specifically targeting renal tubule cells and treating renal fibrosis.
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