- 专利标题: Single-domain antibodies and variants thereof against TIGIT
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申请号: US16958397申请日: 2018-12-28
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公开(公告)号: US11905327B2公开(公告)日: 2024-02-20
- 发明人: Wang Zhang , Shu Wu , Shuai Yang , Qi Pan , Chuan-Chu Chou
- 申请人: Nanjing Legend Biotech Co., Ltd.
- 申请人地址: CN Jiangsu
- 专利权人: Nanjing Legend Biotech Co., Ltd.
- 当前专利权人: Nanjing Legend Biotech Co., Ltd.
- 当前专利权人地址: CN Nanjing
- 代理机构: Fish & Richardson P.C.
- 优先权: WO TCN2017119506 2017.12.28 WO TCN2018097159 2018.07.26
- 国际申请: PCT/CN2018/124979 2018.12.28
- 国际公布: WO2019/129221A 2019.07.04
- 进入国家日期: 2020-06-26
- 主分类号: C07K16/02
- IPC分类号: C07K16/02 ; A61K39/395 ; A61P35/00 ; C07K16/28 ; A61K39/00
摘要:
Provided are constructs comprising a single-domain antibody (sdAb) moiety that specifically recognizes TIGIT. Also provided are methods of making and using these constructs.
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