The present disclosure provides a display substrate and a display device. The display substrate includes a base substrate, and a transistor, an anti-static wire, a first anti-static resistor and a first ground bonding pad on the base substrate, wherein a first terminal of the first anti-static resistor is electrically connected to a first end of the anti-static wire, a second terminal of the first anti-static resistor is electrically connected to the first ground bonding pad, and the first anti-static resistor is at a different layer from a layer at which the anti-static wire is located and a layer at which the first ground bonding pad is located, and is at a same layer as an active layer of the resistor.