- 专利标题： Non-catalytic substrate-selective p38α-specific MAPK inhibitors with endothelial-stabilizing and anti-inflammatory activity, and methods of use thereof
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申请号： US17740248申请日： 2022-05-09
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公开(公告)号： US11911392B2公开(公告)日： 2024-02-27
- 发明人: Paul S. Shapiro , Alexander D. Mackerell, Jr. , Jeffrey D. Hasday
- 申请人： University of Maryland, Baltimore , The United States of America as represented by the Department of Veterans Affairs
- 申请人地址： US MD Baltimore
- 专利权人： UNIVERSITY OF MARYLAND, BALTIMORE,THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- 当前专利权人： UNIVERSITY OF MARYLAND, BALTIMORE,THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- 当前专利权人地址： US MD Baltimore; US DC Washington
- 代理机构： Morgan, Lewis & Bockius LLP
- 主分类号： A61K31/5375
- IPC分类号： A61K31/5375 ; A61K31/18 ; A61K31/54 ; A61P31/00 ; A61P19/02 ; A61P29/00 ; A61P35/00
摘要：
Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.
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