- 专利标题: Fucosylation and immune surveillance in melanoma
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申请号: US16755703申请日: 2018-10-15
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公开(公告)号: US11911404B2公开(公告)日: 2024-02-27
- 发明人: Eric Lau
- 申请人: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- 申请人地址: US FL Tampa
- 专利权人: H. Lee Moffitt Cancer Center and Research Institute, Inc.
- 当前专利权人: H. Lee Moffitt Cancer Center and Research Institute, Inc.
- 当前专利权人地址: US FL Tampa
- 代理机构: Meunier Carlin & Curfman LLC
- 国际申请: PCT/US2018/055810 2018.10.15
- 国际公布: WO2019/075449A 2019.04.18
- 进入国家日期: 2020-04-13
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; A61K31/7004 ; A61K9/00 ; A61K39/395 ; C12Q1/686 ; G01N33/574 ; G01N33/58
摘要:
Disclosed are methods for treating a cancer and/or enhancing immune responses to infiltration of tumors comprising administering to a subject a fucose. Also disclosed herein are methods of detecting the presence of a sugar-modified protein (i.e., a glycosylated protein).
公开/授权文献
- US20200330494A1 FUCOSYLATION AND IMMUNE SURVEILLANCE IN MELANOMA 公开/授权日:2020-10-22
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