- 专利标题: Inhibitors of the interaction between CLEC14A and multimerin-2 for inhibition of angiogenesis
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申请号: US16992497申请日: 2020-08-13
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公开(公告)号: US11919959B2公开(公告)日: 2024-03-05
- 发明人: Roy Bicknell , Peter Noy , Kabir Ali Khan
- 申请人: Cancer Research Technology Limited
- 申请人地址: GB London
- 专利权人: Cancer Research Technology Limited
- 当前专利权人: Cancer Research Technology Limited
- 当前专利权人地址: GB London
- 代理机构: McNeill Baur PLLC
- 优先权: GB 01004 2015.01.21
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; C07K16/30 ; A61P35/00 ; G01N33/50 ; A61K39/00
摘要:
The invention provides a method of inhibiting angiogenesis in an individual, the method comprising administering to the individual an agent that inhibits the interaction between CLEC14A and MMRN2. The inhibitor may be an antibody, a polypeptide, a peptide, a polynucleotide, a peptidomimetic, a natural product, a carbohydrate, an aptamer or a small molecule.
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