Invention Grant
- Patent Title: Fabrication of gold nanoporous anodic aluminum oxide substrate of at-home blood phenylalanine measuring device for phenylketonuria
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Application No.: US18218669Application Date: 2023-07-06
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Publication No.: US11933672B2Publication Date: 2024-03-19
- Inventor: Richard D. Shunnarah , Hugh F. Garvey , Lenzi J. Williams , Devon Fish
- Applicant: MetGen, Incorporated
- Applicant Address: US GA Atlanta
- Assignee: METGEN, INCORPORATED
- Current Assignee: METGEN, INCORPORATED
- Current Assignee Address: US GA Atlanta
- Agency: Locke Lord LLP
- Agent Tim Tingkang Xia, Esq.
- Main IPC: G01J3/02
- IPC: G01J3/02 ; G01J3/44 ; G01N21/65 ; G01N33/52 ; G01N33/68 ; G01N33/50
Abstract:
A method for fabrication of a gold nanoporous anodic aluminum oxide (NAAO) substrate used in coordination with a handheld Surface-Enhanced Raman Spectroscopy (SERS) device for detecting phenylalanine (Phe) in a sample collected from a subject, the method comprising forming a three-phase system on top of a multilayered nanoporous aluminum layer of the gold NAAO substrate; injecting a cosolvent solution into the three-phase system, wherein the cosolvent solution comprises gold nanoparticles; forming a gold layer on top of the multilayered nanoporous aluminum layer, and drying the gold NAAO substrate.
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