This disclosure relates to a system and method to autonomously manage hybrid IT infrastructure. An end-to-end, integrated, and autonomous IT infrastructure is suggested to offload the repetitive business as usual (BAU) operational tasks, thereby reducing operational cost, noise, and chaos, improve resiliency, thus improving availability of the business. The autonomous IT infrastructure leads to bring in efficiency to customer business, to reduce incident reduction, optimize cost and to provide insight into any future IT infrastructure need. Herein, one or more key characteristics that make the IT infrastructure autonomous includes auto sensing an environment of the infrastructure, learning the infrastructure behavior, predicting one or more events, determining a course of action, and performing one or more actions with minimal or no human intervention.