- 专利标题： Gene involved in synthesis of cyclic peptide compound, method for producing cyclic peptide compound using the same, and transformant comprising the same
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申请号： US17549492申请日： 2021-12-13
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公开(公告)号： US11946086B2公开(公告)日： 2024-04-02
- 发明人: Takashi Kubo , Masayuki Machida , Maiko Umemura , Keietsu Abe , Akira Yoshimi , Tomonori Fujioka , Shigenari Yamaguchi , Kiyoshi Kawai
- 申请人： NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY , TOHOKU UNIVERSITY , KUMIAI CHEMICAL INDUSTRY CO., LTD.
- 申请人地址： JP Tokyo
- 专利权人： TOHOKU UNIVERSITY,KUMIAI CHEMICAL INDUSTRY CO., LTD.
- 当前专利权人： TOHOKU UNIVERSITY,KUMIAI CHEMICAL INDUSTRY CO., LTD.
- 当前专利权人地址： JP Sendai; JP Tokyo
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： JP 17000770 2017.01.05
- 分案原申请号： US16476000
- 主分类号： C12N9/10
- IPC分类号： C12N9/10 ; C07K7/64 ; C12N15/80 ; C12P21/02 ; A61K38/10
摘要：
This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.
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