A device may receive, at an operating system, a request for a random number from an application. The device may provide a command to generate an entropy input, based on the request for the random number and through a driver that is isolated from the operating system, to a quantum random number generator that is isolated from one or more processors hosting the operating system. Accordingly, the device may receive the entropy input, from the quantum random number generator, using the driver, and may generate the random number based at least in part on the entropy input. The device may provide the random number to the application.