Invention Grant
- Patent Title: Salt of an aminopyridine derivative compound, a crystalline form thereof, and a process for preparing the same
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Application No.: US17697655Application Date: 2022-03-17
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Publication No.: US11981659B2Publication Date: 2024-05-14
- Inventor: Sang Ho Oh , Jong Gyun Kim , Se-Woong Oh , Tae Dong Han , Soo Yong Chung , Seong Ran Lee , Kyeong Bae Kim , Young Sung Lee , Woo Seob Shin , Hyun Ju , Jeong Ki Kang , Su Min Park , Dong Kyun Kim
- Applicant: Yuhan Corporation
- Applicant Address: KR Seoul
- Assignee: Yuhan Corporation
- Current Assignee: Yuhan Corporation
- Current Assignee Address: KR Seoul
- Agency: BakerHostetler
- Priority: KR 20170051687 2017.04.21
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07C303/22 ; C07C309/04

Abstract:
The present invention relates to novel mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, a novel crystalline form thereof, and a process for preparing the same. More specifically, the present invention relates to mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, which is excellent in stability, solubility, and bioavailability when it is administered not only alone but also in combination with other drugs and which has a high purity, a crystalline form thereof, and a process for preparing the same.
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