Methods and systems to activate beams for beam switching based on measurements of a downlink reference signal that is QCL Type-D with a downlink pathloss reference signal are disclosed. A UE may measure and report to a base station the RSRP of the reference signal that is QCL Type-D with a target downlink pathloss reference signal. Based on the reported RSRP measurements, the base station may activate the target pathloss reference signal to command the UE to update the pathloss measurements of the target pathloss reference signal for uplink power control of a beam corresponding to the target pathloss reference signal. The UE may determine whether the target pathloss reference signal is considered known for uplink power control based on the timing relationship among the reception of the reference signal from the base station, the transmission of the RSRP measurement of the reference signal, and reception of the activation command.