- 专利标题： Anti-cancer plant virus particles linked to HER2 antigens
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申请号： US17039312申请日： 2020-09-30
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公开(公告)号： US11998594B2公开(公告)日： 2024-06-04
- 发明人: Nicole F. Steinmetz , Sourabh Shukla
- 申请人： CASE WESTERN RESERVE UNIVERISTY
- 申请人地址： US OH Cleveland
- 专利权人： CASE WESTERN RESERVE UNIVERSITY
- 当前专利权人： CASE WESTERN RESERVE UNIVERSITY
- 当前专利权人地址： US OH Cleveland
- 代理机构： TAROLLI, SUNDHEIM, COVELL & TUMMINO, LLP
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/295 ; A61K39/39 ; A61P35/00 ; C07K14/005 ; C12N7/00
摘要：
An anti-cancer virus composition including an icosahedral-shaped plant virus or virus-like particle linked to a HER2 antigen is described. The anti-cancer virus composition can be used for methods of treating or decreasing the risk of developing a HER2-expressing cancer in a subject by administering to a subject in need thereof an effective amount of the anti-cancer virus composition.
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