- 专利标题： Tau PET imaging ligands
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申请号： US17450212申请日： 2021-10-07
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公开(公告)号： US12006302B2公开(公告)日： 2024-06-11
- 发明人: José Ignacio Andrés-Gil , Guy Maurits R. Bormans , Lieven Denis Herwig Declercq , Katleen Fierens , Joseph Elisabeth Leenaerts , Diederik Willem Elisabeth Moechars , Frederik Jan Rita Rombouts , Hartmuth Kolb , Wei Zhang
- 申请人： Janssen Pharmaceutica NV
- 申请人地址： BE Beerse
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： BE Beerse
- 代理机构： Ice Miller LLP
- 优先权： EP 204242 2016.12.15 EP 152062 2017.01.18
- 分案原申请号： US16318287
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; A61K51/04 ; C07B59/00
摘要：
The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.
公开/授权文献
- US20220024896A1 TAU PET IMAGING LIGANDS 公开/授权日：2022-01-27
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