Invention Grant
- Patent Title: Liquid chromatograph
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Application No.: US17438419Application Date: 2019-03-13
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Publication No.: US12007373B2Publication Date: 2024-06-11
- Inventor: Tomohiro Gomi , Daisuke Kitabayashi
- Applicant: SHIMADZU CORPORATION
- Applicant Address: JP Kyoto
- Assignee: SHIMADZU CORPORATION
- Current Assignee: SHIMADZU CORPORATION
- Current Assignee Address: JP Kyoto
- Agency: Renner, Otto, Boisselle & Sklar, LLP
- International Application: PCT/JP2019/010420 2019.03.13
- International Announcement: WO2020/183684A 2020.09.17
- Date entered country: 2021-09-11
- Main IPC: G01N30/20
- IPC: G01N30/20 ; G01N30/32 ; G01N30/86 ; G01N30/02

Abstract:
A liquid chromatograph includes a liquid sending pump for sending a mobile phase, a sample injector that injects a sample into an analysis flow path through which a mobile phase from the liquid sending pump flows, a separation column that is provided on the analysis flow path and is to separate a sample that has been injected into the analysis flow path by the sample injector into components, a pressure sensor for detecting a liquid sending pressure in the analysis flow path located at a position farther upstream than the separation column, a damper capacity holder that holds an internal capacity of a system through which a mobile phase from the liquid sending pump flows as a damper capacity, a reference value determiner configured to determine a reference value of a fluctuation range of the liquid sending pressure when a liquid sending failure of the liquid sending pump occurs, using at least the damper capacity held by the damper capacity holder, and a liquid sending failure detector that is configured to periodically acquire a liquid sending pressure detected by the pressure sensor, obtain a fluctuation range of the liquid sending pressure in a certain driving period of the liquid sending pump and detect a liquid sending failure using the obtained fluctuation range and the reference value determined by the reference value determiner.
Public/Granted literature
- US20220146474A1 LIQUID CHROMATOGRAPH Public/Granted day:2022-05-12
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