Invention Grant
- Patent Title: Sustained drug release sheet for treating nerve injury
-
Application No.: US17163871Application Date: 2021-02-01
-
Publication No.: US12016959B2Publication Date: 2024-06-25
- Inventor: Hiroyuki Tanaka , Kiyoshi Okada , Hideki Yoshikawa , Koji Suzuki , Mitsuhiro Ebara
- Applicant: OSAKA UNIVERSITY , NATIONAL INSTITUTE FOR MATERIALS SCIENCE , NIPPON ZOKI PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Suita
- Assignee: OSAKA UNIVERSITY,NATIONAL INSTITUTE FOR MATERIALS SCIENCE,NIPPON ZOKI PHARMACEUTICAL CO., LTD.
- Current Assignee: OSAKA UNIVERSITY,NATIONAL INSTITUTE FOR MATERIALS SCIENCE,NIPPON ZOKI PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Osaka; JP Tsubaka; JP Osaka
- Agency: Oliff PLC
- Priority: JP 16043873 2016.03.07 JP 17008913 2017.01.20 JP 17037270 2017.02.28
- Main IPC: A61K9/70
- IPC: A61K9/70 ; A61K31/714 ; A61K35/36 ; A61K38/18 ; A61K45/00 ; A61K47/32 ; A61K47/34 ; A61K47/36 ; A61P25/02

Abstract:
A sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet including a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.
Public/Granted literature
- US20210205234A1 SUSTAINED DRUG RELEASE SHEET FOR TREATING NERVE INJURY Public/Granted day:2021-07-08
Information query