Invention Grant
- Patent Title: Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors
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Application No.: US17186915Application Date: 2021-02-26
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Publication No.: US12018030B2Publication Date: 2024-06-25
- Inventor: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell , Darby Rye Schmidt , David Joseph Guerin , Justin Andrew Caravella , R. Bruce Diebold , Anna Ericsson , David R. Lancia, Jr.
- Applicant: Valo Health, Inc.
- Applicant Address: US MA Boston
- Assignee: VALO HEALTH, INC.
- Current Assignee: VALO HEALTH, INC.
- Current Assignee Address: US MA Boston
- Agency: Dechert LLP
- Agent Nicholas J. Pace; Steven M. Swick
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; C07D519/00
Abstract:
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula:
where m, n, X1, X2, R1-R5, R5′ and R6 are described herein.
where m, n, X1, X2, R1-R5, R5′ and R6 are described herein.
Public/Granted literature
- US20210332052A1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS Public/Granted day:2021-10-28
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