A method for setting a roll gap of sinusoidal corrugated rolling for a metal composite plate includes steps of: determining entrance thicknesses, exit thicknesses, a width, and a rolling temperature of a difficult-to-deform metal slab and an easy-to-deform metal slab; detecting a roll speed and an entrance speed of a metal composite slab, obtaining a roll radius and friction factors; determining parameters of a sinusoidal corrugating roll and a quantity of complete sinusoidal corrugations on the sinusoidal corrugating roll; then calculating a time required for a complete corrugated rolling; calculating a rolling force at any time during the sinusoidal corrugated rolling of the metal composite plate; and calculating the roll gap S of the corrugated rolling at any time according to the rolling force F, and configuring a rolling mill to have the roll gap S according to an actual rolling schedule before normal production.