- 专利标题： Pharmaceutical composition of a weak acid drug and methods of administration
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申请号： US15930532申请日： 2020-05-13
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公开(公告)号： US12064406B2公开(公告)日： 2024-08-20
- 发明人: Pei Kan , Yi Fong Lin , Ko Chieh Chen
- 申请人： Pharmosa Biopharm Inc.
- 申请人地址： TW Taipei
- 专利权人： PHARMOSA BIOPHARM INC.
- 当前专利权人： PHARMOSA BIOPHARM INC.
- 当前专利权人地址： TW Taipei
- 代理机构： Pilloff Passino & Cosenza LLP
- 代理商 Rachel K. Pilloff; Sean A. Passino
- 主分类号： A61K31/192
- IPC分类号： A61K31/192 ; A61K9/127 ; A61K31/191 ; A61P9/12
摘要：
The present invention relates to a pharmaceutical composition containing liposomes, said liposome comprise an external lipid bilayer; and an internal aqueous medium including a weak acid drug with a half-life of less than 2 hours. Also provided is the use of the pharmaceutical composition disclosed herein to treat pulmonary hypertension with reduced dosing frequency.
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