- 专利标题： Formulations and methods for contemporaneous stabilization of active proteins during spray drying and storage
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申请号： US17508904申请日： 2021-10-22
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公开(公告)号： US12064518B2公开(公告)日： 2024-08-20
- 发明人: Qiyong Peter Liu , Junqing Cui , Rud Karly Lucien , Ryan Carney , Jihae Sohn , Michelle Arya , Abdul W. Khan
- 申请人： Velico Medical Inc.
- 申请人地址： US MA Beverly
- 专利权人： Velico Medical, Inc.
- 当前专利权人： Velico Medical, Inc.
- 当前专利权人地址： US MA Beverly
- 代理机构： Antoinette G Giugliano PC
- 代理商 Antoinette G. Giugliano
- 主分类号： A61K9/16
- IPC分类号： A61K9/16 ; A61K35/16 ; B01J19/06 ; B65D51/30 ; B65D81/26 ; F26B3/04 ; F26B3/06 ; F26B3/12 ; F26B5/04 ; F26B5/06
摘要：
A method of treatment of plasma with a physiologically compatible spray dry stable acidic substance (SDSAS) prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compostions related to plasma dried by the methods of the present invention.
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