Invention Grant
- Patent Title: Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers
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Application No.: US17502170Application Date: 2021-10-15
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Publication No.: US12070491B2Publication Date: 2024-08-27
- Inventor: Toni Weinschenk , Andrea Mahr , Jens Fritsche , Phillip Mueller , Anita Wiebe , Sarah Kutscher
- Applicant: IMMATICS BIOTECHNOLOGIES GMBH
- Applicant Address: DE Tuebingen
- Assignee: Immatics Biotechnologies GmbH
- Current Assignee: Immatics Biotechnologies GmbH
- Current Assignee Address: DE
- Agency: McBee Moore & Vanik IP, LLC
- Priority: GB 23016 2014.12.23 GB 01017 2015.01.21
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K35/17 ; A61K38/04 ; C07K7/00 ; C07K7/06 ; C07K14/435 ; C07K14/725 ; C07K14/74 ; C07K16/18 ; C12N5/0783 ; C12N15/115 ; A61K35/12 ; A61K51/10 ; C07K7/08 ; G01N33/68
Abstract:
A peptide consists of the amino acid sequence IYVTSIEQI (SEQ ID NO: 214) in the form of a pharmaceutically acceptable salt, in which the peptide has the ability to bind to an MHC class-I molecule and, when bound to MHC, is capable of being recognized by CD8+ T cells. A composition contains a peptide consisting of the amino acid sequence IYVTSIEQI (SEQ ID NO: 214), an adjuvant, and a pharmaceutically acceptable carrier.
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