A press-mounting and dismounting machine for multi-gauge and multi-type wheel sets, includes: a frame, a wheel set mounting and dismounting mechanism, and a detection mechanism. The frame includes a base, a first column, a second column and a beam. The wheel set mounting and dismounting mechanism includes a first press-mounting device, a second press-mounting device, a movable baffle device, and a synchronous belt transmission device. The first press-mounting device is arranged on the first column, and the second press-mounting device is arranged on the second column. The synchronous belt transmission device is connected with the movable baffle device to drive the movable baffle device to move in a horizontal direction of the base. The detection mechanism includes a driving rotating device and a data detection device, so as to realize accuracy test of wheel set press-mounting.