- 专利标题: Modified oligonucleotides and methods of use
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申请号: US17063080申请日: 2020-10-05
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公开(公告)号: US12077757B2公开(公告)日: 2024-09-03
- 发明人: Sergei Gryaznov , Leonid Beigelman , Antitsa Dimitrova Stoycheva , Saul Martinez Montero , Jin Hong , Rajendra K. Pandey , Vivek Kumar Rajwanshi , Lakshmipathi Pandarinathan , Yi Jin , Bharat Baral
- 申请人: Janssen Biopharma, Inc.
- 申请人地址: US CA South San Francisco
- 专利权人: Janssen Pharmaceutica NV
- 当前专利权人: Janssen Pharmaceutica NV
- 当前专利权人地址: BE Beerse
- 代理机构: Arnold & Porter Kaye Scholer LLP
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; A61K31/712 ; A61K31/7125 ; A61K47/54 ; A61P31/20 ; C12N15/11 ; C12N15/113
摘要:
Modified oligonucleotides comprising modifications at the 2′ and/or 3′ position(s) along with methods of making and use, e.g., against HBV are disclosed.
公开/授权文献
- US20210040483A1 MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE 公开/授权日:2021-02-11
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