Invention Grant
- Patent Title: Treatment of breast cancer using combination therapies comprising an ATP competitive AKT inhibitor, a CDK4/6 inhibitor, and fulvestrant
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Application No.: US18101377Application Date: 2023-01-25
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Publication No.: US12083129B2Publication Date: 2024-09-10
- Inventor: Kui Lin
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: A61K31/566
- IPC: A61K31/566 ; A61K31/138 ; A61K31/517 ; A61K31/519 ; A61K9/00

Abstract:
Provided herein are combination therapies comprising an ATP competitive AKT inhibitor, fulvestrant, and CDK4/6 inhibitor for use in treating hormone receptor positive and HER2 negative locally advanced unresectable or metastatic breast cancer.
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