Invention Grant
- Patent Title: Quantitative assessment for cap efficiency of messenger RNA
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Application No.: US17746657Application Date: 2022-05-17
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Publication No.: US12084711B2Publication Date: 2024-09-10
- Inventor: Frank DeRosa , Anusha Dias , Michael Heartlein
- Applicant: Translate Bio, Inc.
- Applicant Address: US MA Waltham
- Assignee: TRANSLATE BIO, INC.
- Current Assignee: TRANSLATE BIO, INC.
- Current Assignee Address: US MA Waltham
- Agency: MH2 TECHNOLOGY LAW GROUP, LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07K14/505 ; C12N9/02 ; C12Q1/6823
Abstract:
The present invention provides, among other things, methods of quantitating mRNA capping efficiency, particularly for mRNA synthesized in vitro. In some embodiments, the methods comprise chromatographic methods of quantifying capping efficiency and methylation status of the caps.
Public/Granted literature
- US20220364145A1 QUANTITATIVE ASSESSMENT FOR CAP EFFICIENCY OF MESSENGER RNA Public/Granted day:2022-11-17
Information query
