A massage system for a seat of a vehicle includes a drive motor, a sliding member having a hollow pillar shape, a first end of the sliding member being blocked by a plate member and a second end of the sliding member being opened, a housing member having a hollow pillar shape, a first end of the housing member being blocked by a partition and a second end of the housing member being opened, and a drive gear module operably connected to the drive motor, wherein at least one roller member is extended toward the housing member at an edge of the plate member, and at least one cam protruding toward the sliding member is formed at a circumference of the partition, wherein a cam profile is formed at a surface of the cam.