- 专利标题: Virus and antigen purification and conjugation
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申请号: US17966954申请日: 2022-10-17
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公开(公告)号: US12097256B2公开(公告)日: 2024-09-24
- 发明人: Leigh Burden , Steven D. Hume , Joshua Morton , Greg Pogue , Barry Bratcher , Hugh A. Haydon , Carrie A. Simpson , Nick Partain , John W. Shepherd
- 申请人: KBIO HOLDINGS LIMITED
- 申请人地址: GB London
- 专利权人: KBIO HOLDINGS LIMITED
- 当前专利权人: KBIO HOLDINGS LIMITED
- 当前专利权人地址: GB London
- 代理机构: Wyatt, Tarrant & Combs, LLP
- 代理商 Max E. Bridges; Stephen C. Hall
- 分案原申请号: US16709063 2019.12.10
- 主分类号: A61K39/385
- IPC分类号: A61K39/385 ; C12N7/00 ; A61K39/00
摘要:
Disclosed herein are methods of forming compounds and exemplary compounds in the nature of a conjugated compound demonstrating enhanced stability, which in some embodiments comprises a protein and virus particle mixed in a conjugation reaction to form a conjugate mixture, such that the conditions and steps of forming these products allow for unrefrigerated storage for longer time periods than previous approaches, thus making feasible access to such products over a global supply chain.
公开/授权文献
- US20230056944A1 VIRUS AND ANTIGEN PURIFICATION AND CONJUGATION 公开/授权日:2023-02-23
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