Invention Grant
- Patent Title: Multispecific binders of TGFBeta-superfamily ligands and uses thereof
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Application No.: US17052785Application Date: 2019-05-02
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Publication No.: US12103959B2Publication Date: 2024-10-01
- Inventor: Ravindra Kumar , Dianne S. Sako , Roselyne Castonguay , Tzu-Hsing Kuo
- Applicant: Acceleron Pharma Inc.
- Applicant Address: US MA Cambridge
- Assignee: ACCELERON PHARMA INC.
- Current Assignee: ACCELERON PHARMA INC.
- Current Assignee Address: US MA Cambridge
- Agency: White & Case LLP
- International Application: PCT/US2019/030469 2019.05.02
- International Announcement: WO2019/213442A 2019.11.07
- Date entered country: 2020-11-03
- Main IPC: C07K14/705
- IPC: C07K14/705 ; A61K38/00 ; C07K14/71 ; C07K16/22
Abstract:
In certain aspects, the disclosure provides multispecific binders (e.g., ActRIIA:TβRII heteromultimers comprising an ActRIIA polypeptide and a TβRII polypeptide). The disclosure further provides that such multispecific binders (e.g., ActRIIA:TβRII heteromultimer) may be used to treat various disorders or conditions.
Public/Granted literature
- US20220372107A1 MULTISPECIFIC BINDERS OF TGFBeta-SUPERFAMILY LIGANDS AND USES THEREOF Public/Granted day:2022-11-24
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