Invention Grant
- Patent Title: Metal ion-start DNA polymerase switch and isothermal polymerase amplification method using the same
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Application No.: US17675229Application Date: 2022-02-18
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Publication No.: US12110539B2Publication Date: 2024-10-08
- Inventor: Seung Soo Oh , Hye Bin Yoo
- Applicant: POSTECH Research and Business Development Foundation
- Applicant Address: KR Pohang-si
- Assignee: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
- Current Assignee: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
- Current Assignee Address: KR Pohang-si
- Agency: LEX IP MEISTER, PLLC
- Priority: KR 20210120489 2021.09.09
- Main IPC: C12Q1/6823
- IPC: C12Q1/6823 ; C12Q1/6853 ; C12Q1/686
Abstract:
The present invention relates to a metal ion-start DNA polymerase switch, a composition for isothermal polymerase amplification containing the same, and an isothermal amplification method using the metal ion-start DNA polymerase switch. The metal ion-start DNA polymerase switch according to the present invention may comprise: a binding module composed of TQ30 aptamer; a locking or unlocking module; and a catalytic module connecting between the binding module and the locking or unlocking module and composed of DNAzyme.
Public/Granted literature
- US20230074735A1 METAL ION-START DNA POLYMERASE SWITCH AND ISOTHERMAL POLYMERASE AMPLIFICATION METHOD USING THE SAME Public/Granted day:2023-03-09
Information query
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