Improved spherical beads that may be used in producing pharmaceutically active pellets by depositing a pharmaceutically active agent on the surface of said spherical beads. The spherical beads includes a pharmaceutically acceptable carrier material, including:



a) at least 60 wt. % of phosphoric acid calcium salt and
b) up to 40 wt. % of organic material.




Greater than or equal to 90 wt % of the spherical beads have a particle size in the range of from 90 μm to 1200 μm. The spherical beads have:



a bulk density of at least or more than 1000 g/l,
a specific surface area of at most or less than 10 m2/g, and
a hardness of at least or more than 600 g/mm2. Also included is a method for producing such spherical beads and to pharmaceutically active pellets being prepared by depositing a pharmaceutically active agent on the surface of the spherical beads.