An USB electronic device having functionality of electric leakage protection is discloses. The USB electronic device comprises: a power interface, a power conversion circuit, a system controller, a circuit assembly, and a plurality of USB interfaces, of which the USB interfaces consists of at least one first USB interface and at least one second USB interface, and the first USB interface and the second USB interface both include an electrical terminal for supporting a power delivery (PD) communication protocol. In addition, there is an electric leakage preventing circuit provided in the USB electronic device. As such, in case of a power signal being transmitted between the first/second USB interface and an external electronic device by using the PD communication protocol, the electric leakage preventing circuit is enabled to prevent the power signal has a current leakage occurring between the first/second USB interface and the external electronic device.