Invention Grant
- Patent Title: Transferrin receptor-binding molecules, conjugates thereof and their uses
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Application No.: US17421412Application Date: 2020-01-08
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Publication No.: US12152317B2Publication Date: 2024-11-26
- Inventor: Romy Cohen , Marion David , Michel Khrestchatisky
- Applicant: VECT-HORUS , UNIVERSITE D'AIX-MARSEILLE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Applicant Address: FR Marseilles; FR Marseilles; FR Paris
- Assignee: VECT-HORUS,UNIVERSITE D'AIX-MARSEILLE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee: VECT-HORUS,UNIVERSITE D'AIX-MARSEILLE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee Address: FR Marseilles; FR Marseilles; FR Paris
- Agency: SALIWANCHIK, LLOYD & EISENSCHENK
- Priority: EP19305031 20190109
- International Application: PCT/EP2020/050318 WO 20200108
- International Announcement: WO2020/144233 WO 20200716
- Main IPC: C40B40/10
- IPC: C40B40/10 ; C07K16/28 ; C12N15/10
Abstract:
The invention relates to Variable Domain of Camelid Heavy Chain-only (VHH) molecules which bind TfR and the uses thereof e.g., to transport molecules of pharmaceutical or diagnostic interest into cells and in organs, in pathological conditions including cancer.
Public/Granted literature
- US20220090050A1 TRANSFERRIN RECEPTOR-BINDING MOLECULES, CONJUGATES THEREOF AND THEIR USES Public/Granted day:2022-03-24
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