Invention Grant
- Patent Title: Methods of identifying and treating patients with HIF-2 inhibitor resistance
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Application No.: US18093840Application Date: 2023-01-06
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Publication No.: US12161618B2Publication Date: 2024-12-10
- Inventor: James B. Brugarolas , Haley Hill , Tao Wang
- Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: DLA Piper LLP US
- Main IPC: A61K31/135
- IPC: A61K31/135 ; A61K31/275 ; A61P35/00 ; G01N33/50 ; A61K45/06

Abstract:
The present disclosure provides methods of identifying patients who have partial or total resistance to HIF-2 inhibitors or who develop partial or total resistance to HIF-2 inhibitors after treatment and providing suitable treatment to these patients.
Public/Granted literature
- US20230293474A1 METHODS OF IDENTIFYING AND TREATING PATIENTS WITH HIF-2 INHIBITOR RESISTANCE Public/Granted day:2023-09-21
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