Disclosed embodiments relate to devices and systems for providing both negative-pressure therapy and instillation, In some embodiments, both negative-pressure and instillation may be provided to a tissue site in a low-profile context that may also prevent siphoning of instillation fluid during negative pressure application. For example, a single bridge may include a negative-pressure pathway with supports and an instillation pathway, and the instillation pathway may be configured with respect to the negative-pressure pathway so that at least a portion of the instillation pathway collapses upon application of negative pressure to the negative-pressure pathway. Collapse of at least a portion of the instillation pathway may be sufficient to close the instillation pathway.