Invention Grant
- Patent Title: Enhanced immune cells using dual shRNA and composition including the same
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Application No.: US17701535Application Date: 2022-03-22
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Publication No.: US12285438B2Publication Date: 2025-04-29
- Inventor: Chan Hyuk Kim , Young-Ho Lee , Yujean Lee , HyeongJi Lee , Sang Hoon Lee
- Applicant: CUROCELL INC. , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Daejeon; KR Daejeon
- Assignee: CUROCELL INC.,KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: CUROCELL INC.,KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Daejeon; KR Daejeon
- Agency: Sheppard, Mullin, Richter & Hampton LLP
- Priority: KR10-2018-0004238 20180112
- Main IPC: A61K31/7088
- IPC: A61K31/7088 ; A61K38/17 ; A61K39/00 ; A61K39/395 ; A61P35/00 ; C07K14/47 ; C07K14/705 ; C07K14/725 ; C07K16/28 ; C12N5/0783 ; C12N15/113
Abstract:
The present disclosure is broadly concerned with the field of cancer immunotherapy. For example, the present invention generally relates to an immune cell comprising a genetically engineered antigen receptor that specifically binds to a target antigen and a genetic disruption agent that reduces or is capable of reducing the expression in the immune cell of a gene that weakens the function of the immune cell.
Public/Granted literature
- US20220348871A1 ENHANCED IMMUNE CELLS USING DUAL SHRNA AND COMPOSITION INCLUDING THE SAME Public/Granted day:2022-11-03
Information query
