发明申请
- 专利标题: ESTERS OF 5-AMINOLEVULINIC ACID AS PHOTOSENSITIZING AGENTS IN PHOTOCHEMOTHERAPY
- 专利标题(中): 5-氨基酸在光化学疗法中作为光敏剂使用
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申请号: US09471620申请日: 1999-12-21
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公开(公告)号: US20010051743A1公开(公告)日: 2001-12-13
- 发明人: KARL E. GIERSKCKY , JOHAN MOAN , QIAN PENG , HARALD STEEN , TROND WARLOE , ALF BJORSETH
- 优先权: GB9525822.4 19951218; GB9504948.2 19950310
- 主分类号: C07C229/00
- IPC分类号: C07C229/00 ; A61K031/24 ; A01N037/12 ; A01N037/44 ; A61K031/22 ; A01N025/00
摘要:
The present invention relates to compounds being esters of 5-aminolevulinic acids or pharmaceutically acceptable salts thereof, including compounds of formula (I) R22NnullCH2COCH2nullCH2COnullOR1 (wherein R1 may represent alkyl optionally substituted by hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino, aryl, oxo or fluoro groups and optionally interrupted by oxygen, nitrogen, sulphur or phosphorus atoms; and R2 represents a hydrogen atom or a group R1, and both R2 groups may be the identical or different), and their use in diagnosis and photochemotherapy of disorders or abnormalities of external or internal surfaces of the body, and products and kits for performing the invention.
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