Invention Application
US20020019536A1 NEW URETHANES, THIO AND DITHIO ANALOGUES AND THEIR USE AS INHIBITORS OF CHOLESTEROL BIOSYNTHESIS
有权
新URETHANES,THIO和DITHIO ANALOGUES及其作为胆固醇生物合成酶的抑制剂
- Patent Title: NEW URETHANES, THIO AND DITHIO ANALOGUES AND THEIR USE AS INHIBITORS OF CHOLESTEROL BIOSYNTHESIS
- Patent Title (中): 新URETHANES,THIO和DITHIO ANALOGUES及其作为胆固醇生物合成酶的抑制剂
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Application No.: US09275318Application Date: 1999-03-24
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Publication No.: US20020019536A1Publication Date: 2002-02-14
- Inventor: ROLAND MAIER , RUDOLF HURNAUS , MICHAEL MARK , BERNHARD EISELE , PETER MUELLER , GEBHARD ADELGOSS , GEBHARD SCHILCHER
- Priority: DE19754795.8 19971210
- Main IPC: C07D223/04
- IPC: C07D223/04 ; C07D211/22 ; C07D211/24 ; C07D27/14 ; C07C271/06 ; C07C317/42

Abstract:
The present invention relates to urethanes and the thio and dithio analogues thereof of general formula 1 wherein m, n, A, X, Y and R1 to R8 are defined as in claim 1, the enantiomers, diastereomers and the salts thereof, particularly the physiologically acceptable acid addition salts thereof which have valuable properties, particularly an inhibitory effect on cholesterol biosynthesis, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
Public/Granted literature
- US06346545B1 Urethanes, thio and dithio analogues and their use as inhibitors of cholesterol biosynthesis Public/Granted day:2002-02-12
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