Invention Application
- Patent Title: Benzofuran derivatives, their preparation and use
- Patent Title (中): 苯并呋喃衍生物，其制备和用途
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Application No.: US09874392Application Date: 2001-06-04
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Publication No.: US20020032205A1Publication Date: 2002-03-14
- Inventor: Kim Andersen , Mario Rottlander , Klaus Peter Bogeso , Henrik Pedersen , Thomas Ruhland , Robert Dancer
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby-Copenhagen
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby-Copenhagen
- Priority: DKPA199801631 19981209
- Main IPC: A61K031/496
- IPC: A61K031/496 ; C07D49/02 ; A61K031/4525 ; A61K031/352
Abstract:
The present invention relates to benzofuran derivatives having general Formula (I) 1 wherein A is selected from (1), (2), (3), (4) 2 wherein Z is O or S; s is 0 or 1; q is 0 or 1; R4 is hydrogen, C1-6-alkyl, C2-6-alkenyl, C26-alkynyl, C1-6-alkyl-aryl, or C1-6-alkyl-O-aryl; D is a spacer group selected from branched or straight chain C1-6-alkylene, C2-6-alkenylene and C2-6-alkynylene; its enantiomers, and pharmaceutically acceptable acid addition salt thereof. The compounds are potently binding to the 5-HT1A receptor.
Public/Granted literature
- US06492374B2 Benzofuran derivatives, their preparation and use Public/Granted day:2002-12-10
Information query
