Invention Application
- Patent Title: Process for the stabilization of proteins in complex mixtures during their storage in aqueous solvents
- Patent Title (中): 复杂混合物中蛋白质在水性溶剂中储存期间稳定化的方法
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Application No.: US09991964Application Date: 2001-11-26
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Publication No.: US20020058623A1Publication Date: 2002-05-16
- Inventor: Franz-Josef Rubroder , Reinhold Keller
- Applicant: Aventis Pharma Deutschland GmbH
- Applicant Address: null
- Assignee: Aventis Pharma Deutschland GmbH
- Current Assignee: Aventis Pharma Deutschland GmbH
- Current Assignee Address: null
- Priority: DE19930676.1 19990702
- Main IPC: A61K038/28
- IPC: A61K038/28 ; C12P021/02
Abstract:
The present invention relates to a process for the storage of proteins in an aqueous solution. The addition of cysteine delays the temporal decrease in the effective concentration of the protein. The process is suitable for use in the production of heterologous proteins in microorganisms.
Public/Granted literature
- US06734164B2 Process for the stabilization of proteins in complex mixtures during their storage in aqueous solvents Public/Granted day:2004-05-11
Information query
