Invention Application
US20030065154A1 Interleukin-8 homologous polypeptides and therapeutic uses thereof
审中-公开
白细胞介素-8同源多肽及其治疗用途
- Patent Title: Interleukin-8 homologous polypeptides and therapeutic uses thereof
- Patent Title (中): 白细胞介素-8同源多肽及其治疗用途
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Application No.: US10015967Application Date: 2001-12-07
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Publication No.: US20030065154A1Publication Date: 2003-04-03
- Inventor: Dan L. Eaton , Dorothy French , J. Christopher Grimaldi , Kenneth J. Hillan , Maria Teresa Pisabarro , Kerstin N. Schmidt , Victoria Smith , Daniel Tumas , Richard Vandlen , Colin K. Watanabe , P. Mickey Williams , William I. Wood
- Applicant: Genentech, Inc.
- Applicant Address: null
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: null
- Priority: USPCT/US01/06520 20010228; USPCT/US00/08439 20000330; USPCT/US00/23328 20000824
- Main IPC: C07H021/02
- IPC: C07H021/02 ; C07H021/04
Abstract:
The present invention is directed to novel polypeptides having structural homology to IL-8 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treatment and diagnosis of inflammatory diseases.
Public/Granted literature
- US07291712B2 Interleukin-8 homologous polypeptides and therapeutic uses thereof Public/Granted day:2007-11-06
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