发明申请
- 专利标题: Sphingolipids
- 专利标题(中): 鞘脂
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申请号: US10273664申请日: 2002-10-17
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公开(公告)号: US20030133904A1公开(公告)日: 2003-07-17
- 发明人: Arieh Dagan , Shimon Gatt
- 主分类号: A61K031/74
- IPC分类号: A61K031/74 ; C08G063/48 ; C08G063/91 ; A61K031/785
摘要:
The invention relates to compounds of the general formula (I), as defined, and to pharmaceutical compositions containing them. The compounds of formula (T) are inhibitors of various lipid-related enzymes. They can be used in reducing accumulation of sphingolipids and thus in the treatment of lipid storage diseases. The compounds of formula (I) can also be used for the treatment of cancerous diseases and for killing of wild type and drug-resistant cancer cells.
公开/授权文献
- US06756504B2 Sphingolipids 公开/授权日:2004-06-29